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The compound reaches peak plasma concentration approximately 12 to 72 hours after subcutaneous injection, then gradually declines over the following days

However, the trial duration was only 24 weeks, and longer-term data may show different patterns

This represents a novel area of treatment at the overlap between the inflammatory and metabolic nexus, potentially leading to better outcomes in uncontrolled asthma

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Medical societies, including the American Medical Association, have formally acknowledged that BMI is an imperfect measure of adiposity and metabolic health